DPCstruct | MC23574

Metacluster Properties and Pfam Annotations

Number of structural domains7465
Mean domain length (aa)149 ± 28 aa
Standard deviation of domain lengths27.55
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score76.94
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)14.19
Pfam Score75.44
Assigned Pfam label(s) PF18701- CL0194- PF05380- PF02238- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A395ILC7 160-309 None
A0A395IJP1 428-585 None
A0A395ICC5 212-372 None
A0A4Q9MD27 270-429 None
A0A453T131 10-161 None
A0A6P3ZS03 120-240 None
A0A3A6TKW4 87-258 None
A0A395J283 155-306 None
Q84UZ3 636-774 None
A0A317XP08 89-252 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.