DPCstruct | MC23574

Metacluster Properties and Pfam Annotations

Number of structural domains7465
Mean domain length (aa)149 ± 28 aa
Standard deviation of domain lengths27.55
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score76.94
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)14.19
Pfam Score75.44
Assigned Pfam label(s) PF18701- CL0194- PF05380- PF02238- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A561SA84 16-183 None
A0A438ICN1 1032-1199 None
A0A438ICN2 9-126 None
A0A438I8Q4 703-865 None
A0A438I7A5 297-530 None
A0A1I4RIF3 18-163 None
A0A4Q3USR8 2-173 None
L9KL27 179-381 None
A0A4Y2NUG5 12-131 None
A0A4Y2NTJ3 115-239 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.