DPCstruct | MC23574

Metacluster Properties and Pfam Annotations

Number of structural domains7465
Mean domain length (aa)149 ± 28 aa
Standard deviation of domain lengths27.55
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score76.94
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)14.19
Pfam Score75.44
Assigned Pfam label(s) PF18701- CL0194- PF05380- PF02238- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A699IGT7 134-249 None
A0A699IF49 2-122 None
A0A699IEG8 7-130 None
A0A1V5Y8S4 101-246 None
I1BL01 119-261 None
A0A1A2ANP8 1-166 None
A0A674J656 2-97 None
H3HA23 466-628 None
H3H6Q7 349-523 None
H3H627 162-295 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.