DPCstruct | MC23574

Metacluster Properties and Pfam Annotations

Number of structural domains7465
Mean domain length (aa)149 ± 28 aa
Standard deviation of domain lengths27.55
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score76.94
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)14.19
Pfam Score75.44
Assigned Pfam label(s) PF18701- CL0194- PF05380- PF02238- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A328VZL1 18-185 None
A0A6P6R1S9 77-245 None
A0A6P6QNT1 19-166 None
H3BBN4 355-532 None
H3B8L7 304-462 None
H3B6Z0 188-354 None
H3AMH6 224-407 None
W5LVJ2 38-213 None
A0A1U7WVK6 124-292 None
A0A1U7WT45 17-173 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.