DPCstruct | MC23574

Metacluster Properties and Pfam Annotations

Number of structural domains7465
Mean domain length (aa)149 ± 28 aa
Standard deviation of domain lengths27.55
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score76.94
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)14.19
Pfam Score75.44
Assigned Pfam label(s) PF18701- CL0194- PF05380- PF02238- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A1IXB0 4-119 ERGIATDGAHSMKRGVTRYRAVDLGTGELLFEQNIGNQTINIGEFLGVVEAAKYIIEHRFSPAIIYTDSLTALTWFNEKRTASRKRN…
M5WZF6 21-165 IFNRAHHLAEKSTKWSPPPAGKYKLNVDAAFIPETGVGGIGAVVRNDKGEVMAAMALPLASATSSKHAEIMAFLFGMKFARDAGCSS…
A0A2V1DED3 43-183 None
A0A2C9VZN5 210-322 None
A0A1I3ZA38 4-155 None
A0A0R3URP1 12-186 None
A0A1R3KN67 11-151 None
A0A803QCN7 288-435 None
A0A1M7AVM0 52-188 None
I1CM16 88-219 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.