DPCstruct | MC2355

Metacluster Properties and Pfam Annotations

Number of structural domains345
Mean domain length (aa)233 ± 69 aa
Standard deviation of domain lengths68.57
Length coefficient of variation0.29
Mean AlphaFold2 pLDDT confidence score89.72
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)21.11
Pfam Score90.72
Assigned Pfam label(s) PF10232- CL0063- PF09298- CL0032- PF02615

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0L8HZY4 7-337 AWCEARATLQKMLSASEATLKDDVGLRQKAFVPQNKAKMHLPARIGDYTDFYSSKNHAYNVGCMFRGPENALMPNWTYLPVGYHGRA…
A0A7J7B617 296-578 SRTCPRLHALSESLNNDSADGVFDLDHQALAAPLPRAYEFVDGSAYLPHVERVRRARNAEVPASFYTDPLMYQATSASFYGPRDPVC…
A0A2H3G5Y6 47-271 None
A0A4Z0YTF3 797-1115 None
A0A819NEE5 14-197 None
A0A6V8HJG0 633-1013 None
A0A160U7I9 2-165 None
K8EPP4 144-420 None
A0A672UMV8 71-276 None
A0A3E0DNT3 30-230 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.