DPCstruct | MC2354

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)183 ± 15 aa
Standard deviation of domain lengths15.48
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score74.15
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)27.91
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H1CLE8 25-196 RLRQEEERDVDLLVNDLSDWVGVILKFEGILNWENPGLLVAILLLVTSVFMLFHLYSPTVLCTIGCFGLALSTIDYFGPTVSARLSH…
A0A7J7B5B8 2-187 DDQETQTSILKDSFESWKEIILLVHSVLLWEKNWYPGAILGGTSFLFLTLWLVDASILSTLSILGLTITISDYVVPIVAAVMFKPES…
A0A3B0K2I9 5-175 None
A0A5N5TFL3 3-209 None
A0A7R9NZM3 40-218 None
A0A6A5DAL7 196-400 None
D3PIR8 5-187 None
A0A151N172 9-203 None
D6X2T5 35-225 None
A0A1D1VJP9 235-417 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.