DPCstruct | MC23536

Metacluster Properties and Pfam Annotations

Number of structural domains65
Mean domain length (aa)141 ± 26 aa
Standard deviation of domain lengths25.71
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score68.54
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)30.40
Pfam Score77.72
Assigned Pfam label(s) CL0229- PF01754

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J8IV69 9-171 PGPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQQNSGRMSPMGTASGSNSPTSDSASVQRADASLNNCEGAAGSTSEKSRNVPVAAL…
A0A3M0K112 17-136 GCGFYGSPRTNGMCSVCYKEFLQRQQSSDRISPPGTLLEISQNTAESKTASEKPKPKKNRCFTCRKKIGLTGFDCRCGNLFCAIHRY…
A0A6A6LH73 33-172 None
M8B4E4 109-269 None
A0A6J3CDX8 109-244 None
A0A445HS49 237-390 None
A0A5N6Q5G7 1-134 None
A0A1B0C3F7 551-671 None
A0A6A6N919 2-127 None
A0A337SV80 1-234 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.