DPCstruct | MC2352

Metacluster Properties and Pfam Annotations

Number of structural domains464
Mean domain length (aa)130 ± 26 aa
Standard deviation of domain lengths25.97
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score86.93
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)19.06
Pfam Score95.76
Assigned Pfam label(s) CL0264- CL0063- CL0080- PF19648- CL0292

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
N4VU66 155-300 KPDFAGGKLRCLCKTRPVEVTLGSNVAHNHACGCSKCWKPPGALFSVVGVVPREHVSVTANADKLRVVDDAAVILRNACRECGAHLF…
A0A7J7AX02 246-363 AAGSCLCGGIHYEVHGEIGPVIQCHCKRCRKANGTAFATNAPIQKADFKIVKGESLLKQFASTETTTRCFCQECGSPIISIKAEAPE…
A0A194V2T5 2-122 None
A0A2U8G815 1-91 None
A0A1J9S403 9-138 None
A0A1D3DE17 2-118 None
A0A318YN56 41-178 None
A0A496Q330 15-122 None
A0A535A059 210-358 None
A0A4S2MZ63 54-173 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.