DPCstruct | MC23498

Metacluster Properties and Pfam Annotations

Number of structural domains325
Mean domain length (aa)188 ± 27 aa
Standard deviation of domain lengths26.56
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score88.25
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)20.18
Pfam Score69.57
Assigned Pfam label(s) CL0023- CL0113- CL0123- CL0061- PF16861

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J2VD64 11-176 NPDPLILDKAAKILRSGGIVAFPTETVYGLGGVVYNEDAVKKIFWAKKRPIDNPLIVHVSSLSMLEEVAVSIPEKAYLLIERFWPGP…
A0A2N3GXL9 11-200 NPSAEAINLAATVLREGGIVVFPTETVYGIGASANSCIGPQEIIDIKMRPKNKPLPWLVESEEALDTYGVDVPDYAHRLARAFWPGA…
A0A7C5Z468 133-335 None
X6J8X3 2-140 None
A0A803PWQ1 451-648 None
A0A1F3W7V9 136-340 None
A0A1Y2H3T5 112-310 None
A0A0K9R128 319-522 None
A0A518HJL2 444-644 None
A0A7E4W4V7 15-217 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.