DPCstruct | MC23494

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)216 ± 18 aa
Standard deviation of domain lengths18.45
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score86.94
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)35.91
Pfam Score100.00
Assigned Pfam label(s) PF12127

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W4VBW8 2-185 GMRLRRVVPSRVINPLIKATKAGINVSINKLEAHYLAGGNVDRVVNALIAAQRANIPLEFERAAAIDLAGRNVLEAVQMSVNPRVIE…
A0A2E9G4W0 4-228 VTILIFWFLGLITFFIFLFFVPVNLWLTALSAGVYVSLFKIIKMRTARVPPRIIVDSLINARKSGIKLSDDRLSEHYLAGGHVPHVV…
A0A660VYF4 1-233 None
A0A7X9TCB5 2-193 None
A0A7C6QQ74 14-228 None
B5JKW3 1-191 None
A0A2C6MA73 2-219 None
A0A5C6BYK6 15-255 None
A0A1W9MNQ1 1-229 None
A0A419EV84 165-400 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.