DPCstruct | MC23486

Metacluster Properties and Pfam Annotations

Number of structural domains439
Mean domain length (aa)136 ± 31 aa
Standard deviation of domain lengths30.61
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score83.83
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)13.00
Pfam Score61.48
Assigned Pfam label(s) CL0010- CL0248- PF20233

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1J9QRB5 27-172 QTVAREQWPDFFSAGKIFRIKISDGTLRVYVIVEPGERSSTCLMIKTYSGQATTRPDVRDRQNEHAVIYTMAQPPKPLRGEDKLRRP…
A0A0B5B089 26-163 KYAKKEKSMMEFPKRGDIWTLDFGQGVGSEMRGTRPVVVLSSSLTNEKTNTLLVLPITKHSGTEESERNTDFIFHLPLTPDLLKWGG…
K2S9K4 185-336 None
A0A2V4WHN3 2-119 None
A0A087Q9T8 9-134 None
A0A6M1LGE7 2-116 None
A0A7G6T632 6-114 None
A0A538Q208 29-150 None
A0A412J2H0 61-180 None
A0A395WC71 41-145 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.