DPCstruct | MC23461

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)168 ± 23 aa
Standard deviation of domain lengths23.13
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score87.12
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)19.81
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A7BNE6 3-177 DLAGLESVFKTYGVSTIKVESNGNLTLPVTESLSFSLRPNIESSPAWEGMSLGLHTQPTTLPGVLTFMLVFKDENGSLRQQNLYPAA…
A7BLP1 20-195 IENPAALQTALIEWGLVRFEMGSDGNLSISGDPQFKIRPDLFSRITDASLALGLDWKTSPLLSGLNQLVFRFQDKTGAHREQVFYPV…
A0A2A5B161 586-749 None
A0A251X3U1 440-607 None
A0A496V5P6 305-439 None
A0A0Q8TDD3 132-293 None
A0A1F4CX03 244-403 None
A7BVI4 139-316 None
A0A3C0P7U4 422-596 None
A7BST5 181-348 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.