DPCstruct | MC2346

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)151 ± 23 aa
Standard deviation of domain lengths23.22
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score79.01
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)32.57
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6G0GU60 71-207 GSKVIKSNDDLNIEQYNGVNKIGKPSGHGYAFEDINNRNIRKTGCKVDSSIGKTCEKGGADAVVTDKDGNSFEVQYKCTSSAKLAAD…
A0A4Q6H9R3 2-148 KLPETWSTNEKMFASGGQGHGFAAERGNHIVDRVRLKNARILGDNNARNGADRLVSGTEIQTKYCSTAARSVGAAFDGQNGQYRYMG…
N1ZGI7 402-525 None
A0A521F0N3 3-166 None
A0A125PCS0 26-162 None
A0A1H6P2Q5 22-206 None
A0A8B3DN79 390-572 None
A0A376VJJ4 125-272 None
A0A231PVK5 298-442 None
A0A482IMM6 13-162 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.