DPCstruct | MC23434

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)376 ± 30 aa
Standard deviation of domain lengths29.64
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score85.66
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)38.99
Pfam Score100.00
Assigned Pfam label(s) CL0113

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A420YHX6 233-612 GPALNTLYLGISAVFADDHTAVVALAIHDTVYLIDFSVKHIVLDDALKLGDDLIADYIINEVEKYEHENFAKFIGAGLPTTLKYMSP…
A0A397G5G9 29-411 NTIWAGFSELIEEGSKTRIAIVIRNSTYLLDCVIHEWEERASRDPAEISHEIISQLQNYSAKYMEKFIGAGLPESLVLKCPGLCSQL…
A0A1Y2IB02 37-452 None
A0A178F3H5 32-406 None
W9NWI3 37-412 None
A0A094KNQ6 44-437 None
A0A1J8QPR2 36-453 None
A0A421DHL9 556-964 None
A0A428TPC6 34-335 None
A0A093VDU6 31-417 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.