DPCstruct | MC2328

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)186 ± 31 aa
Standard deviation of domain lengths31.31
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score80.84
Mean fraction of residues predicted as intrinsically disordered0.42
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)41.54
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A096MAR3 160-310 KGRRKARKTDASDLTPNPQKLHNIGEQLQKLNAAIKGMGPVNDLPAVARARSRKEKNKLASRACRLKKKAQHEANKIKLWGLNQEYE…
A0A2M4C5Y5 20-185 LFPPRFADNSTKNLRLQHSGKARKGDGNDLTPNPRKLHNIGKELDKLGRVINDMKPVSELPFNVRPKTRKEKNKLASRACRLKKKAQ…
A0A1W0XFE3 240-456 None
A0A131ZXQ0 214-446 None
A0A7J7JDT0 291-485 None
A0A7R9QFL9 508-721 None
A0A182QWS0 653-875 None
A0A2B4SCW8 282-446 None
T1EZ76 605-802 None
A0A6P6XM00 1083-1258 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.