DPCstruct | MC23268

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)123 ± 11 aa
Standard deviation of domain lengths10.83
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score76.17
Mean fraction of residues predicted as intrinsically disordered0.45
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)36.90
Pfam Score87.50
Assigned Pfam label(s) CL0125- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L5MH15 1-145 MSLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLEKKEAMLFPSENEKISKQLHLCYNIVKDHYVRVSD…
A0A0S7I7C3 1-129 MKRQQSLSPDRKRELTERLLVELVEFISPKTPKPGELGGRSSGSLAWRIARGETRAADKKTEAFVFKPTDEEKKARLLHMRYSAPKD…
A0A183D535 106-218 None
A0A444U1R1 172-285 None
A0A811JSN1 369-481 None
A0A7R9CKR1 422-548 None
A0A1I8GXR7 249-369 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.