DPCstruct | MC23222

Metacluster Properties and Pfam Annotations

Number of structural domains342
Mean domain length (aa)196 ± 33 aa
Standard deviation of domain lengths33.24
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score88.95
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.69
Pfam Score96.90
Assigned Pfam label(s) PF00596- PF10120- CL0118

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W7TPD7 177-399 None
A0A7V6ZPU0 43-223 None
A0A7J2ZCK4 13-180 None
A0A5A8CKV8 189-413 None
A0A4Z2B587 82-284 None
A0A6P4ING1 105-326 None
A0A365NNV0 430-624 None
A0A1E7ELM4 436-641 None
A0A4S9HAR9 2-221 None
A0A6P7TPH0 32-240 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.