DPCstruct | MC23222

Metacluster Properties and Pfam Annotations

Number of structural domains342
Mean domain length (aa)196 ± 33 aa
Standard deviation of domain lengths33.24
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score88.95
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.69
Pfam Score96.90
Assigned Pfam label(s) PF00596- PF10120- CL0118

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A846KDF7 1-119 LNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATIWAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERK…
A0A1J4NV45 5-187 DDHGDPVWGHVSQRDPDGRGVWLKTGPRGFDEVAADDVALVDLDGRLLEGSGPPPREYPLHTEVLRARGDINSVVHCHPPYSIALAA…
A0A120E8G7 630-855 None
A0A7R9ARQ8 6-166 None
A0A2G9LRE7 108-274 None
A0A1Y2T8X3 5-185 None
A0A370V1R2 1-149 None
A0A2P4ZPA9 12-239 None
A0A2D6J1Q0 20-161 None
A0A1F3ETD0 15-262 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.