DPCstruct | MC23213

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)118 ± 13 aa
Standard deviation of domain lengths12.63
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score89.14
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)42.60
Pfam Score100.00
Assigned Pfam label(s) CL0229

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A8IYN4 1-131 EEEAACCWLCLGGAEDEGAGPLVAPCRCPRVCHPACLSRWQLHCAGRKEEKACRFCGEQLPDWRQATRFSSLFCIHKIRVMPGPDGT…
A0A150GMQ5 25-143 MCWICLDDTKDKDPLINPCKCPRKVHPRCLARWQLQQAGRLEETNCRFCQCNLADWKTSLTPENLKPEVQRVQPIMVVYFEGQIHRI…
A0A7S1SMH6 58-173 None
A0A0D2NPK6 18-120 None
A0A835Y580 12-124 None
A0A2J8A6Q3 1-147 None
A8JCQ1 2-121 None
A0A2J7ZR38 2-120 None
E1ZE12 2-99 None
A0A061R770 34-143 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.