DPCstruct | MC23143

Metacluster Properties and Pfam Annotations

Number of structural domains908
Mean domain length (aa)175 ± 28 aa
Standard deviation of domain lengths27.52
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.96
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)14.93
Pfam Score97.14
Assigned Pfam label(s) CL0023- CL0378- CL0016- CL0149- CL0091

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A395S194 245-419 None
A0A1K1SWW9 13-289 None
A0A8A8M7J6 98-274 None
A0A7H4LK70 21-196 None
A0A2V7Z7D4 382-558 None
A0A378U9L6 234-399 None
A0A1Z5TKV5 217-389 None
A0A7G1IBT6 26-228 None
A0A7G1IKX7 87-254 None
A0A4D8YJ17 19-193 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.