DPCstruct | MC23143

Metacluster Properties and Pfam Annotations

Number of structural domains908
Mean domain length (aa)175 ± 28 aa
Standard deviation of domain lengths27.52
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.96
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)14.93
Pfam Score97.14
Assigned Pfam label(s) CL0023- CL0378- CL0016- CL0149- CL0091

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Z3UPQ4 29-205 None
A0A7Y6ABU0 114-294 None
A0A5A7S8K8 625-800 None
A0A2C5Z1D1 12-149 None
A0A6P8AWK5 554-730 None
A0A6P8BF64 108-294 None
A0A816JQ11 92-227 None
A0A2C6AKQ1 440-606 None
A0A6G1NAL5 29-130 None
A0A2D4STI5 23-155 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.