DPCstruct | MC23143

Metacluster Properties and Pfam Annotations

Number of structural domains908
Mean domain length (aa)175 ± 28 aa
Standard deviation of domain lengths27.52
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.96
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)14.93
Pfam Score97.14
Assigned Pfam label(s) CL0023- CL0378- CL0016- CL0149- CL0091

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6G1IXE5 217-404 ARPLGLVEYSFDTDGTEYGGRADMNSLLTLETSHTLPSKEDFRRRIALAWASLRLQHPMLTSRTVENAETLGRSFVVDVCESAEEVV…
E3RZQ1 9-171 ILPVTHSQKIYLCRGLDDPRVAFNHFYVDIGPQLDLELLRDSCRKLVDHFSILRTKFVPHKQEWFQIVLRTLELPFSVFDVDQSMDE…
A0A0F7SBP9 160-315 None
A0A194ULN6 4-154 None
A0A2P9IBG7 467-641 None
A0A1K2CK94 35-199 None
A0A1D9FLV2 322-566 None
A0A5E4ESX7 38-235 None
F6H6F0 163-345 None
A0A2G7GLA6 453-635 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.