DPCstruct | MC23117

Metacluster Properties and Pfam Annotations

Number of structural domains30
Mean domain length (aa)144 ± 16 aa
Standard deviation of domain lengths15.55
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score84.18
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)24.54
Pfam Score91.23
Assigned Pfam label(s) PF17408- CL0257

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V8GNG2 1-158 MNDQPRRFLQRVWDSVRQPPSVTASHAADTLVGLCDSLLSERGEVSGARMAGEAMAAYQELNDAGRGAFFGQLVDHYTADPDAVTRA…
A0A2P5KTU8 460-589 FIERARVHADALMSERGEVLGTVISHDLVRLVRSATSSERLEFLSMLSKRFAPDPKAISVAADRWRLEPSEANRASLAAAVEAPRQE…
A0A1S3JV45 37-167 None
A0A5N5MZM2 67-196 None
A7T5Q1 30-171 None
A0A162ULQ6 79-224 None
A0A446U9B5 19-176 None
A8TKZ1 4-131 None
A0A2B4RZ80 48-200 None
A0A2Y9P609 37-195 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.