DPCstruct | MC231

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)134 ± 17 aa
Standard deviation of domain lengths16.57
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score85.53
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)42.52
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A833VY84 1-124 MLHEGCLKHRESVITSDFGRTGDKDSQVGRFQRDDKNLRQKLEKCPDVEIYLPSSIRGDGYCEDAMGYVKYLQGRALPRWVLDVEFE…
T0QTN5 64-192 RNETQGDDLFGDIVHLNNLNEACFHANDSIVHWAFNSSEVNHTELWTRDATPRDELIAHLAQCPEVDVFLPAGLRDHGYCEDGMAYV…
A0A6A3KXA5 49-171 None
A0A3F2RLZ2 283-443 None
A0A067BUA3 74-196 None
A0A833SU12 38-200 None
A0A3R7BNQ1 29-157 None
A0A3L6UNX2 36-176 None
A0A418ECS6 13-157 None
A0A418C0B9 43-142 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.