DPCstruct | MC23096

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)82 ± 5 aa
Standard deviation of domain lengths5.41
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score91.06
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.93
Mean intra-cluster sequence similarity (%)74.55
Pfam Score100.00
Assigned Pfam label(s) PF00223

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S8I2Y4 267-351 SKYAEFLTFRGGLDPITGGLWLTDIAHHHLAIAILFLIAGHMYRTNWGIGHGIKDILEAHKGPFTGQGHKGLYEILTTSWHAQLS
A0A2Z2C6A9 98-182 SKYAEFLSFRGGLDPITGGLWLSDIAHHHLAIAILFLIAGHMYRTNWGIGHGLKDILEAHKGPFTGQGHKGLYEILTTSWHAQLS
A0A453LHU2 267-351 None
A0A2J6MDN1 254-335 None
A0A4D6M3U4 569-653 None
A0A4D6LEZ3 427-511 None
A0A889Q3Q3 46-127 None
T2JVS6 254-335 None
A0A2U1PTW1 572-652 None
B9RX98 74-144 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.