DPCstruct | MC23091

Metacluster Properties and Pfam Annotations

Number of structural domains82
Mean domain length (aa)143 ± 28 aa
Standard deviation of domain lengths28.39
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score82.63
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)42.25
Pfam Score98.25
Assigned Pfam label(s) CL0063- PF04043- CL0588

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S7MVL1 3-120 RKMKLPGREGKTAVVVGTITDDVRIQEVPKLKVCALRVSSRARSRILKAGGKILTFDQLALDSPKGCGTVLLSGPRKAREVYRHFGK…
A0A2K5CLN6 1-141 MGVDIRHYQDRKDIYLRLLVKLTNYTFTQIVLKMLFMSCTNRPPLSLSRMIQKMKLPRRENKTAMVVGTITDDVRIQEVPKLKVCAL…
A0A821HTB2 8-176 None
A0A0D3CMJ2 30-210 None
A0A1R3K845 949-1121 None
R9PFR9 157-312 None
A0A1V6NZK7 353-522 None
A0A445CE28 18-141 None
A0A2I0I861 9-135 None
A0A6A3B0U2 98-304 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.