DPCstruct | MC23078

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)173 ± 27 aa
Standard deviation of domain lengths26.84
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score67.73
Mean fraction of residues predicted as intrinsically disordered0.44
Mean length-normalized TM-Score0.25
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)36.85
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0C9R2Z3 1-174 MKAFIILLATVATSLASPGYLYGYAPLGHDGRVVDTPEVAHAKAEHLAAHAKEASKHALSYGYGPGYAPEVSYGGHHDNIKYHGPPA…
A0A7M7MM05 4-137 TRHLLLLALSCLVLAASGAAAGYVAPYVAPYHGPPAPLAHDGRVIDTPEVAHAKAVHLATHAAEAAKASPSATAYDDYEGKYEGNGG…
E2C2I4 2-142 None
A0A833VUA2 98-239 None
A0A7E4RCY2 17-235 None
A0A3L8DFW4 1-163 None
F4WD93 68-226 None
A0A6P3DH49 26-195 None
A0A7E4RCZ8 1-173 None
A0A834JHE6 1-214 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.