DPCstruct | MC23075

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)97 ± 11 aa
Standard deviation of domain lengths10.62
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score89.02
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)36.49
Pfam Score91.67
Assigned Pfam label(s) CL0036- CL0108

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4W5LVB0 1-93 MAGKPLVSRDSFNHIGVGNASLCQEVVRRIFNFSSCSFSRCSFNGVYQPPLQGPFGAFSAFYFVMNFLNLTSDSLESSREKLARYCS…
A0A2G9RS75 112-218 TADLYSSPCVSDRRILTIPQTIQIKGTGNYQLCKDKVENIFNLSHCSYSRCSFNGIFQPMLQGEFGAFSAFYFVMDFLKVTKEKVSL…
A0A6J3GJX4 216-307 None
A0A2B4S6S3 292-406 None
A0A821IPC0 1-93 None
A0A3P7KXI6 193-275 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.