DPCstruct | MC23062

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)157 ± 14 aa
Standard deviation of domain lengths14.38
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score79.07
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)25.91
Pfam Score100.00
Assigned Pfam label(s) CL0175

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2T4ADW1 10-157 GFIRPERGGCGICGRETSRRCQACSLDWFCSQECQDQMSFNHLTLCSARSITTADKLWHYAVGDRIPQDSETREHFGFTRCRGWRDE…
A0A166WRG6 1-137 MAERECGNPKCNEPATRRCSACTDRRGWYCSERCQRKAWPLHIFDCNTTKPAKTAYHMAIASLLNIPPPHWQTKQDYGFSKLSPEDQ…
A0A6A6CJR3 606-757 None
A0A2B7XXS5 87-246 None
A0A1Y6M0H5 56-224 None
A0A6A6AYA7 512-659 None
A0A1G4ATH7 32-215 None
A0A066XG44 35-215 None
A0A4Q9MA98 46-169 None
A0A397SA81 2-134 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.