DPCstruct | MC23054

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)124 ± 10 aa
Standard deviation of domain lengths9.87
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score84.78
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)31.99
Pfam Score87.88
Assigned Pfam label(s) PF00057- PF02931

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0P4WEH7 223-343 VFNGARLSRIEWRDNSTWVLYQMDNPFIRAHMLVSTDTGYPVGVHDYEVIGDKCPGKVQRLKLTSCRGNTFTCGDGECIDISRRCNL…
A0A6A0GZG6 54-182 YESVNNRPSLAGYLHSDIFWNNETKEWTLTSRKTPDALALYKPDEPSDYPFGKKMWQVESPICGYSKGEKVLLTLSACSSGKYSCDD…
A0A7R8CI81 198-332 None
A0A7R8D5S4 6-135 None
A0A0N7ZCC6 314-436 None
A0A0P4VR73 304-423 None
A0A0P4WCH5 160-284 None
A0A0P4W890 106-223 None
A0A5B7J0M4 1-140 None
A0A0P4VXJ7 77-192 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.