DPCstruct | MC23028

Metacluster Properties and Pfam Annotations

Number of structural domains395
Mean domain length (aa)212 ± 43 aa
Standard deviation of domain lengths42.87
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.33
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)16.43
Pfam Score86.40
Assigned Pfam label(s) CL0125- CL0734- CL0040- PF10210- CL0010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C3P967 10-211 IVRLGTVDSTQLEARRWLGGPEAASTPQGGGRMFIAREQTAGRGRLGRAWQSPPGGLWTTIAWNSPELQNREGRESGAWIERLGIRL…
T2S9Z6 5-153 EKRVFESLPSTQTYLLEKLKNDELKAPILVVAKNQSAGIGSRGNVWESVKSALTFSLALNASDLPKDLPMQANALYLGFLFKEVLKE…
A0A2G8L5L8 18-257 None
A0A3S0ZQT7 11-260 None
A0A1Q9CL49 602-847 None
A0A066V7W3 51-362 None
A0A563VJA5 3-126 None
A0A2H6KEA1 262-516 None
A0A0D3CHI2 145-366 None
A0A0D8XKB2 794-1029 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.