DPCstruct | MC23007

Metacluster Properties and Pfam Annotations

Number of structural domains73
Mean domain length (aa)213 ± 29 aa
Standard deviation of domain lengths28.76
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score85.15
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)13.26
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T2DMV0 2-214 PKDMDDFLDFILNELGEGTWVPLYKNLNKEDKSEDGSLYSCLVSPGNTQKAMEGYGWDLLPGSGGPSIVSSGKDNIWYEPNSSEYLP…
A0A1P8LXB6 237-458 WVVLESVIKQVDPQARKGWRGLREQAAVDTLLIAADAAEEFLTDLPDDPHHQIPDLFDSHGHTGCCYVGEVGRVGGSCCHRHDQLRP…
A0A134AFA2 191-379 None
R5FW99 324-558 None
A0A521DNA5 7-228 None
A0A519Q4U6 21-204 None
A0A378N6F1 470-706 None
N9PCD2 329-581 None
A0A7W6Y201 456-691 None
A0A849QPP3 288-521 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.