DPCstruct | MC2299

Metacluster Properties and Pfam Annotations

Number of structural domains103
Mean domain length (aa)67 ± 8 aa
Standard deviation of domain lengths8.30
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score71.84
Mean fraction of residues predicted as intrinsically disordered0.57
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)31.31
Pfam Score100.00
Assigned Pfam label(s) PF00172

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y3MYT7 29-83 NSNSNDNEIEKKESKRKKVSQACENCRKKRRKCSGDRPKCITCQQNNYICYYNPC
D8QGE1 2-62 SQSANSSMSALNYDGPRVPRRTPMACEFCRRKLKCDGGRPSCANCEKKKFPCNYVPVYVPS
M2N156 64-129 None
A0A1J8PM84 358-439 None
A0A1B7Y7L7 1-58 None
A0A1L9U837 1-69 None
A0A127Z8T3 2-67 None
A0A842Z0N5 1-66 None
A0A438NFQ1 1-64 None
A0A2V1D679 4-68 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.