DPCstruct | MC22984

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)120 ± 13 aa
Standard deviation of domain lengths13.06
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score77.06
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)26.40
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A172XRJ3 1-114 MCTPNTELQFCTCVEGDIYEVKDIYIWTLSMYIDSKKSMIRGKIMKSTEDFENGISAENIISKLNEENIFDFEYTPKERDTLHISFN…
A0A2T6C565 1-150 MCEVSKTIKFCSCKDNLSEAHKHAKSMYYVWTLERVTGLSELAMDGLLMEEPTQLDELSAEKIVKELNSKNLFDFDYQPINDDTLEI…
A0A376GC90 17-127 None
A0A1G7BDK7 1-120 None
A0A2U0DMV7 1-107 None
K2Q414 1-117 None
A0A6S6TK49 17-136 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.