DPCstruct | MC22973

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)127 ± 11 aa
Standard deviation of domain lengths11.21
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score94.19
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)35.62
Pfam Score90.00
Assigned Pfam label(s) CL0137- CL0257

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0K2REB2 2-115 GDRLDTDILGGNRAGFATAAVLTGVDTPESILAARSSERPGYLLADLTELYEPYPEIVEEDSTFRCGKATAEVQDGLITVSGSEKDL…
X8CVI8 2-126 IGDRLDTDIEGANAAELPSLMVLTGVNSARDAVYAKPAQRPTYIGHDLRSLHADAERLAVGPQPGWRVDVADGAITVSGDGPDDGDG…
A0A838H7N1 151-270 None
A0A0K2R0J3 23-152 None
A0A3N4G725 519-662 None
A0A849BTV7 233-367 None
A0A6B2DU32 83-203 None
A0A4D4M4H5 17-136 None
A0A077LYX6 98-217 None
A0A5S4ZLR0 17-152 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.