DPCstruct | MC22967

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)90 ± 7 aa
Standard deviation of domain lengths7.44
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score88.58
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)36.73
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A379LSE5 3-103 HFKLGYAGKHGVGGAAGVLPSPYTKAGRQMRDRLASLGVLRESTKQDHFRGCVVVPIIGWSGAASVGQRERVMQLYGRRSVEDAKVN…
A0A5C5W9M1 48-132 LDQFRIGYANRTLGLKLPGKHLKSGKQIRGRLEALNIFRPKSGHEQFNGCVVFPIQSPDGTGRIVDIYGRKTGSHLRKGTPLDMF
A0A7I8BJ85 1-92 None
A0A5C5ZIM3 42-123 None
A0A516HCR8 71-153 None
B9NWZ6 24-114 None
Q84BA2 161-263 None
A0A848A0X0 157-240 None
A0A3A3FF67 158-245 None
A0A0Q0CVF9 47-130 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.