DPCstruct | MC22964

Metacluster Properties and Pfam Annotations

Number of structural domains191
Mean domain length (aa)121 ± 15 aa
Standard deviation of domain lengths15.34
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score86.18
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)16.46
Pfam Score10.71
Assigned Pfam label(s) CL0301- PF18906- PF02924- CL0373- PF07195

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2W5TRK2 1072-1206 None
A0A1C5P0C0 97-199 None
A0A7J7JUE3 1-153 None
G6XIS2 38-160 None
A0A7S1G5U6 18-162 None
A0A7K0A4Q0 27-143 None
A0A645APU7 9-110 None
A0A2D6M712 179-313 None
A0A2D6MC27 49-178 None
A0A2D6MHC8 7-144 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.