DPCstruct | MC22964

Metacluster Properties and Pfam Annotations

Number of structural domains191
Mean domain length (aa)121 ± 15 aa
Standard deviation of domain lengths15.34
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score86.18
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)16.46
Pfam Score10.71
Assigned Pfam label(s) CL0301- PF18906- PF02924- CL0373- PF07195

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3C2CG97 100-222 IEPDTVKATGTLTLAVQPTVGDTLTIGANTYTFVAAGTAGAVGEVSVGDDLAGAKLALVGVINGTDGLNTSHPLVSASAFVGDVCTL…
A0A2X2FEE6 6-122 IEDAAAGKKASATLTITAPATRGGTLSLFVCGERLDIPVETADTVSVLNQAVVDIVNANTHLPLVAALTGEANGTVTLTARQSGDWG…
A0A7D5S0L9 91-215 None
A0A1G3M002 80-197 None
A0A1F5QSV0 71-180 None
A0A1F5QTK7 13-127 None
A0A848L7M4 587-709 None
A0A2D7XB49 144-270 None
A0A0F9GTE6 5-136 None
A0A0F9MXZ0 77-190 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.