DPCstruct | MC22961

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)146 ± 16 aa
Standard deviation of domain lengths15.57
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score85.09
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)22.60
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R8FS63 2-134 KAIWISVLDNPHPLKFIDPTNEQQCAWAWEYLQKHGVSMSIFHPTNNREEYLSAVASIDLNPSHRDTKKIFLMSMKKAYDQKKYREK…
A0A2K8JZW8 257-399 RVVFIETRTHPKDLEWIDKSNHSQLIWAIDYLKKNNFLISPLNFYPNDAKQMFAQICASIDLIAIREKIASGNLAYSPIQELFLQKM…
A0A827TXK0 18-191 None
A0A3D8GXR9 46-182 None
A0A3A6RSW4 5-148 None
A0A7D6WLT6 112-288 None
A0A1X0VWR8 197-336 None
A0A6D0R4E0 2-119 None
A0A483NEM3 148-309 None
A0A6H1Y5N2 162-296 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.