DPCstruct | MC2296

Metacluster Properties and Pfam Annotations

Number of structural domains32
Mean domain length (aa)363 ± 68 aa
Standard deviation of domain lengths67.80
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score78.35
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)22.65
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A135SMI7 34-461 KLRDALGKPIDLAFAYTCKRVADEMRGLALEANTITASTFYSPDERHRARDFDLVTMMLNEELENALHCSQHLLWDDTCDDISGAFP…
A0A6G1JM91 18-475 QPVGLDLAYACKIAANEMRGIPFRTNKIKSTVGSSNNHQGGHRGLQSRAGRFRCLLKYAQETQLRMAFHIAELMTPQVLQSLEELVI…
A0A1L7W9F2 98-493 None
A0A010S011 388-717 None
I1S3A3 26-327 None
A0A1B7XZW0 57-498 None
A0A2H3H6V1 39-466 None
A0A2P4ZF21 79-542 None
A0A6A5U5H0 2-398 None
W7N2U6 6-354 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.