DPCstruct | MC22948

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)108 ± 11 aa
Standard deviation of domain lengths11.39
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score89.47
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)54.67
Pfam Score100.00
Assigned Pfam label(s) CL0040

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A822AJ17 2-106 KRILPQIGNMNAAGLDQLVKQYHIKAPNTNNDLSEPIAFNLMFSTTIGATGQVKGYFRPEAAQGMFVNFKRLLEFNQGRLPFAAAQI…
A0A4V3SGZ9 1-92 MRSPATNNELSEPQQFNLMFATMIGPTGQCQGYLRPETAQGIFVNFQRLLQFNQGRIPFGAAQIGSAFRNEISPRSGLIRVREFAMA…
A0A6V8HPU0 429-549 None
A0A445AMK7 53-146 None
A0A3Q0KEV1 177-297 None
A0A822YG00 199-303 None
A0A183L9Y6 257-358 None
A0A6Q8PH49 240-344 None
A0A1L9UB14 155-275 None
A0A6I9YKN6 59-163 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.