DPCstruct | MC22939

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)163 ± 20 aa
Standard deviation of domain lengths20.24
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score85.20
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)27.29
Pfam Score100.00
Assigned Pfam label(s) PF05140

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q2JNP5 8-179 LARWVSSLRRYFRHELLPLLADLRLAIGLLLAIAVLSATGTVIEQEETAAFYQAHYPEHPALFGFLTWRVILSLGLDHVYRTPWFLA…
A0A2H1KHX2 34-205 APADIGFVGLLRWAWRQLTTMRAALILLLMLALAIIPASLLPQRIQDPARVASFIEDNGQWGEVLDTFQLFDVHSSVWFASIYILLM…
A0A265Q619 8-165 None
A0A1A3T902 1-136 None
A0A0K2RN18 62-217 None
A0A1V1P5B2 10-170 None
A0A1V1W802 10-181 None
A0A1H3B6D5 10-143 None
I0Z470 398-594 None
A0A1V3WF26 1-137 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.