DPCstruct | MC22932

Metacluster Properties and Pfam Annotations

Number of structural domains74
Mean domain length (aa)116 ± 16 aa
Standard deviation of domain lengths15.55
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score81.86
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)41.68
Pfam Score100.00
Assigned Pfam label(s) PF05669

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q6GQA1 10-116 EQHRIRFQLELEFVQCLANPNYLNFLAQRGYFKDKSFVNYLKYLLYWKDPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFID…
A0A060THA1 3-102 LWWSNKFIQSLANPQYLNFLAQSKYLESEEFLNYLNYLEYWREPENAKYLIYPNCLHVLTLLKEPRFRQEISRADVAKMFMDDFYMT…
A0A438E1W4 200-319 None
A0A0V0Y6A7 4-114 None
A0A5N5K2T5 73-209 None
D4DDC7 97-239 None
A0A813M9S5 283-389 None
F2SDI9 2-115 None
A0A5N6PFL5 13-135 None
A0A6A3B1T0 15-146 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.