DPCstruct | MC22918

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)126 ± 8 aa
Standard deviation of domain lengths8.13
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score89.51
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.91
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)51.46
Pfam Score100.00
Assigned Pfam label(s) CL0111

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5C6NFD7 51-168 AGLLAACFIAIVPGYISRSVAGSFDNEGIAIFALQFTYYLWVKSVKTGSVFWTIGCCLSYFYMVSAWGGYVFIINLIPLHVFALLLM…
A0A0R3SM85 15-128 VAGSYDNEGIAIFALLLTYFLWLRAVRTGHLLWSVLCALAYLYMVSAWGGYVFIINLVPLHAFVLCLTGRYSSRLYVAYTSFYILGL…
A0A812XF59 523-652 None
A0A813FJU4 2-129 None
A0A2T7PF01 463-591 None
A0A5J4W627 129-262 None
A0A7I8VU91 649-778 None
A0A1Q9D9W9 561-693 None
A0A504XK01 496-626 None
A0A2V2WVS8 200-334 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.