DPCstruct | MC2290

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)155 ± 5 aa
Standard deviation of domain lengths4.85
Length coefficient of variation0.03
Mean AlphaFold2 pLDDT confidence score86.14
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)25.31
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5Q4ENT3 596-743 FVPWRDYRVYMSNLDEDLRGRIIGVPGVRSDRPNLDLGSRFEVVITRNILTYFLLPIACTLFRTVNIMGCDGRPLKENDYFWRHDPS…
A0A1V4PY97 1-154 MIVQSEFRAVESLLVPVPWGEHTNIAVDLNDQFFLPDVENVLANLLLPLGCSLSRDVRMWGFDGRGPSDSGFWANSDRHAYPELMQS…
A0A202DBW5 44-196 None
T2JL49 1-159 None
A0A5A9F7L0 72-225 None
A0A267MHZ2 456-607 None
A0A522A4K8 256-407 None
A0A2D6PQM3 352-516 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.