DPCstruct | MC22874

Metacluster Properties and Pfam Annotations

Number of structural domains102
Mean domain length (aa)132 ± 24 aa
Standard deviation of domain lengths23.59
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score90.38
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)25.50
Pfam Score100.00
Assigned Pfam label(s) PF11303

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D6KC01 4-111 PVGGDHNPVWQNCNGDVYTAPIENEHAVHALEHGAVWVTYNAKAAKADVAALAEKVRRTPYTLMSPVADQKDPIMLSAWAHQRSVSG…
A0A6I5WIU4 13-123 QVRYNSQPPTSGPHFAFSLAPGRYTVAVPEGLAVHAMEHGHVIILYAETTPESTIADLERVAKRHADKVVLAPSEKLSDGIAMTAWG…
A0A6J4HLN2 26-160 None
A0A7W0WAV5 170-322 None
A0A1I0FUE4 48-199 None
A0A350XP62 292-427 None
A0A7R9L0W7 17-155 None
A0A518LIM3 150-283 None
E7F4B0 50-193 None
A0A258H948 2-86 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.