DPCstruct | MC22868

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)256 ± 40 aa
Standard deviation of domain lengths39.58
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score82.59
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)40.60
Pfam Score57.54
Assigned Pfam label(s) CL0007- CL0237- PF12072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3D0UXB5 33-252 QKEVDEIVQQQVTKLSELAHLSKDDAKKQLMDQVEQEYQSDFTAFIEKLKNVKKEEADKEAAMIVSKSLPRVAVDSVSEFTTKTVDL…
X1S686 42-300 ENRLAQKTESLERKLEGLEHRERNLGNQEKKIESTRSQLEEVRNRQLRQLELISGMSSAEAKQTLLETMEVEIQEEASRRLREWEAK…
A0A2V5X0L0 209-520 None
A0A835G3E7 53-358 None
A0A061NW83 3-227 None
A0A0G0EJE0 11-306 None
A0A7V3EQL5 86-387 None
A0A0G0S545 43-342 None
A0A7X1E7W7 66-291 None
A0A4Y8I2G4 1-258 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.