DPCstruct | MC22841

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)248 ± 20 aa
Standard deviation of domain lengths19.51
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score84.62
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)36.58
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y9YZ11 117-339 MERIRELYELRFSTINPVVDLIDRCVGVQWYATPNFWDGGVDDAWTLNMDPPETFFHLATYGELFAPAFDTFLDTGVVPEAMDVDTR…
A0A1Q3E6E3 1-221 MAGEQWYQADNFWNGGVSEPATLQTESNRAAYQIIIYSELFASTMEAYLEPKKNLPKFDLGVRLDYIKYCIPDWTCRSYPGLEVLSV…
A0A225AS64 115-393 None
B8NPT3 111-351 None
A0A1L7WYL9 110-342 None
A0A6A6Z4Q0 1-269 None
A0A084BCE4 111-364 None
A0A5M9MAL5 110-351 None
W2RQX2 113-378 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.