DPCstruct | MC22832

Metacluster Properties and Pfam Annotations

Number of structural domains52
Mean domain length (aa)173 ± 32 aa
Standard deviation of domain lengths32.12
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score80.96
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)28.54
Pfam Score100.00
Assigned Pfam label(s) CL0175

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C7YN37 31-157 TGLKDGSYLYNRSERDVFRILIDCFRLRLEEQSQHDKKGAEGTIYAGADDSLPAFRQFLELAATREDLLPPWWTPEKQRECEEFGMS…
A0A1B8DH04 29-174 LMRCAKCLTALYCSLECFQAMNDMFGLSNDDFLHDRPEGEVFNLLIDSFRMRVEDESVYGGNTIGVYNGENILPLFKKFLSLAESRQ…
A0A5C5FTD1 13-206 None
A0A438MY20 210-395 None
A0A6G1IT08 8-166 None
W9WLK3 8-156 None
A0A1V6T2Z0 59-265 None
A0A1Y2CBV6 33-225 None
A0A6A5QIS1 72-259 None
A0A0F4Z6B8 150-350 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.